SARS-COV-2 infection after double vaccination is associated with a reduced risk of developing long COVID symptoms at least 12 weeks later. This highlights the importance of public health initiatives to increase vaccination at the population level. However, scientists warn that studies with longer follow-ups are needed to assess the impact of booster doses and the Omicron variant and to assess symptom trajectories much further than 12 weeks. This is especially important given the relapsing nature of long COVID.
Daniel Ayoubkhani, Matthew L Bosworth, Sasha King, Koen B Pouwels, Myer Glickman, Vahé Nafilyan, Francesco Zaccardi, Kamlesh Khunti, Nisreen A Alwan, A Sarah Walker, Risk of Long COVID in People Infected With Severe Acute Respiratory Syndrome Coronavirus 2 After 2 Doses of a Coronavirus Disease 2019 Vaccine: Community-Based, Matched Cohort Study, Open Forum Infectious Diseases, Volume 9, Issue 9, September 2022, ofac464, https://doi.org/10.1093/ofid/ofac464